A young father takes his nine year old son, the family dog, and two of his son's friends backpacking in the mountains of Colorado only for all five of them to be struck by lightning.
Returning series regulars include Sarah Jessica Parker, Cynthia Nixon, Kristin Davis, Sara Ramírez, Sarita Choudhury, Nicole Ari Parker, Karen Pittman, Mario Cantone, David Eigenberg, Evan Handler, Christopher Jackson, Niall Cunningham, Cathy Ang and Alex
分属善恶两个截然对立的阵营，天使亚茨拉斐尔（麦克·辛 Michael Sheen 饰）却和恶魔克劳利（大卫·田纳特 David Tennant 饰）在长达六千年的相处过程中培养出超凡寻常的默契和友情，两人各自在职责范围内左右着人间世界的发展走向，相互补位，默契十足。自从成功阻挠末世之战后，亚茨拉斐尔与克劳利短暂过上了一段安宁舒适的生活。可是这一天，一名不速之客闯入亚茨拉斐尔的书店，宣告着新的危机的产生。来者正是大天使加百列（乔恩·哈姆 Jon Hamm 饰），只不过他似乎忘记了自己的身份以及来到人间的目的
