Upon moving into her husband's childhood home to help take care of his elderly relatives, Jean Copeland, an emotionally withdrawn wife and mother of two, becomes embroiled in an affair with a suicidal lover. Her husband, Gordon, is oblivious, too busy worrying that he's losing his most prized possession, his mind, after a run-in with an ex-girlfriend he doesn't remember. 19-year-old, Priscilla, is a fashionista desperate to become a reality TV star, while 9-year-old crossword fanatic, Otis, has fallen in love for the very first time. Otis falls in love with Caterina after, well, forever. With Gordon's father, Theodore, fading into dementia, and 95-year old matriarch, Vivian, desperately clinging to control of the house, the six family members, at five stages of life, distill the dreams, worries, and regrets, of contemporary America.